Monitoring Uterine Health (MUH)

Oculyze Monitoring Uterine Health is a quick & easy tool to detect subclinical or cytological Endometritis through automatically identifying inflammatory cells (PMNs). Turn your smartphone or tablet into a powerful on-farm lab by simply connecting it to the Oculyze mobile fluorescence microscope.

How it works

Direct on-farm detection

Results within minutes

Zero laboratory knowledge needed

Step #1

Extract a sample from the uterus with a cytobrush or cytotape and smear it onto a conventional microscopy slide.

Step #2

Stain the sample with one drop of fluorescent dye and wait for two minutes.

Step #3

Connect the microscope with your mobile device and open the Oculyze app.

Step #4

Take as many images as you need to capture about 300 cells. Depending on the sample quality this may take 10 to 20 images.

Step #5

Immediately review analysis results directly in the app and check for the PMN level.

Frequently asked questions

Yes, there is an option to connect your existing fluorescence laboratory microscope. For more information and individual support please reach out to us via our contact form.
A sample of a healthy cow usually contains mainly endometrial cells and only very few inflammatory cells (PMNs). In contrast, a sample from a cow suffering from subclinical or cytological endometritis contains a lot of inflammatory cells. From day 21 p.p., subclinical or cycological endometritis is confirmed when a sample with at least 300 cells contains more than 5% PMNs. In the MUH App, those cells will be automatically highlighted in red. Usually, 10-20 images are required to be able to classify cows as healthy or sick. However, cows with a very high amount of inflammatory cells (e.g. clinical cases) may be already diagnosed after only a few images.
The actual quantification of cells is done within seconds. The whole analysis process, including sample staining and image capturing, takes on average 5 minutes. However, the time needed for taking a sample can vary and highly depends on the experience of the person taking the sample and the anatomy of the cow.
If you do not already have a supplier for the sampling equipment, you need help to find one, or if you would prefer to use a self-made tool, please reach out to us via our contact form for individual support.
We recommend testing not before day 21 p.p. (as inflammatory cells are part of the physiological recovery after calving) and as close to the anticipated insemination day as possible. It might also make sense to match the sampling with other check ups that are regularly being performed on your farm. Additionally, repeat breeders should be considered to be checked right before insemination.
The sampling process is the most critical part of the analysis and might require some training. However, veterinarians or persons experienced in A.I. should be able to take a sample easily. The analysis of the sample can be done by everyone on the farm as there is no expert knowledge required.